Author

Erli You

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

H. Eric XuiD· 2 shared Hualiang JiangiD· 2 shared Jingjing ShiiD· 2 shared Shuyang ZhangiD· 2 shared Wanchao YiniD· 2 shared Xiaodong LuaniD· 2 shared Yi JiangiD· 2 shared Chunyou MaoiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMolecular Biology

H. Eric XuORCID

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2 papers

Recent·Most cited

Structures of full-length glycoprotein hormone receptor signaling complexes

Jia Duan, Peiyu Xu, Xi Cheng, Chunyou Mao, Tristan Ian Croll, Xinheng He, Jingjing Shi, Xiaodong Luan, Wanchao Yin, Erli You, Qiufeng Liu, Shuyang Zhang, Hualiang Jiang, Yan Zhang, Yi Jiang, H. Eric Xu

The paper reports cryo-EM structures of LHCGR in different activation states, revealing a push and pull mechanism of receptor activation and the role of an allosteric agonist.

bioRxiv · Aug 3, 2021 · PreprintMolecular Biology

Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19

Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao, Xiaoxi Wang, Fulai Zhou, Jingjing Shi, Erli You, Mingliang Liu, Qingxia Wang, Qingxing Wang, Yi Jiang, Hualiang Jiang, , H. Eric Xu

The paper discovers suramin as a potent inhibitor of SARS-CoV-2 RNA polymerase and provides its structural mechanism for repurposing in treating COVID-19.

bioRxiv · Oct 6, 2020 · PreprintMolecular Biology