Author

Rene Keil

Institute of Molecular Medicine, Martin Luther University Halle-Wittenberg, Halle, Germany;ORCID 0009-0006-2804-6934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alice Wedler-GeyeriD· 2 shared Andrea SinziD· 2 shared Frank HauseiD· 2 shared Oleksandr SorokiniD· 2 shared Stefan HuettelmaieriD· 2 shared Christian H. IhlingiD· 1 shared Dirk Taenzler· 1 shared Laura Schian· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Alice Wedler-GeyerORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 2, 2026

Local fractal dimension as an indicator of functional reorganization in molecular interaction networks

Frank Hause, Alice Wedler-Geyer, Marcell Lederer…·Stefan Huettelmaier

The paper introduces DIFFRACT, a framework that uses local fractal dimension changes in protein interaction networks to detect functional reorganization, showing its utility in identifying novel biological roles in RAVER1-deficient cells.

DOI 10.64898/2026.10.27.762149

E. coliArabidopsis

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BioinformaticsNAR Genomics and BioinformaticsPeer-reviewedOct 7, 2025

CENTRA: Knowledge-Based Gene Contexuality Graphs Reveal Functional Master Regulators by Centrality and Fractality

Frank Hause, Alice Wedler, René Keil…·Stefan Hüttelmaier

CENTRA uses gene co-occurrence networks from literature to identify functional master regulators by analyzing centrality and fractality in topic-specific contexts.

DOI 10.1093/nargab/lqaf196

statistical modelgene regulatory network inference

𝕏 PostBluesky