Alice Wedler

The paper introduces DIFFRACT, a framework that uses local fractal dimension changes in protein interaction networks to detect functional reorganization, showing its utility in identifying novel biological roles in RAVER1-deficient cells.

This study identifies IGF2BP1 as a regulator of mitotic integrity in CRC, showing that its inhibition creates a therapeutic vulnerability that synergizes with paclitaxel.

CENTRA uses gene co-occurrence networks from literature to identify functional master regulators by analyzing centrality and fractality in topic-specific contexts.

This study shows RNA-seq-derived sequence variations can reliably identify cell lines and detect cross-contamination using machine learning.

This study identifies FAM30A as a regulator of LSC function in AML by interacting with MSI2 and RUNX1, enhancing stemness and chemoresistance.

This paper investigates RAVER1's role in controlling alternative splicing and its impact on miR/RISC activity and EMT in cancer cells.