Eleni Christakou

The paper presents a structural analysis of the AXL-tilvestamab complex using cryo-EM and SAXS, providing a low-resolution 3D model and insights for optimizing binding affinity.

This study maps the paratope residues of tilvestamab, an anti-AXL antibody, identifying twelve critical residues and Glu2 on AXL essential for binding.

This paper characterizes two anti-Arc nanobodies that bind to the ligand-binding pocket of human Arc-NL, revealing their structural and functional properties as competitive inhibitors.