Ionic strength modulates structural disorder and protein oligomerization in the marginally disordered Phd transcription factor
Uroš Zavrtanik, Gopinath Muruganandam, Maruša Prolič-Kalinšek, Dietmar Hammerschmid, Frank Sobott, Alexander N. Volkov, Remy Loris, San Hadži
This paper shows how ionic strength affects the structural disorder and oligomerization of the Phd transcription factor, revealing its ability to function as a conformational rheostat.
bioRxiv · Apr 17, 2026 · PreprintBiophysics