Author

Sheikh Omar Kunjo

Fred Hutch Cancer CenterORCID 0009-0006-4646-9762Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:experimental assay· 1

Frequent Co-Authors

Brenda J Chen· 1 shared Irini TopalidouiD· 1 shared Katherine S. YanagiiD· 1 shared Nicolas J. LehrbachiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Brenda J Chen

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1 paper

Recent·Most cited

Molecular BiologyPLoS GeneticsPeer-reviewedAug 10, 2026

Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function.

Katherine S. Yanagi, Brenda J Chen, Sheikh Omar Kunjo…·Nicolas J. Lehrbach

This study identifies the critical role of lysine deficiency in EEL-1/HUWE1 for maintaining UPS function by enhancing ubiquitination of pre-ubiquitinated substrates.

1 citation

C. elegansexperimental assay

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