Author
Gladstone InstitutesORCID 0009-0006-4731-6047Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Rahul K. Suryawanshi, Priyadarshini Jaishankar, G. J. Correy…·James S. Fraser
This study identifies Mac1 as a therapeutic target for SARS-CoV-2 and demonstrates that AVI-4206, a small molecule inhibitor, reduces viral replication and improves survival in an animal model.
Tyler C. Detomasi, Gilles Degotte, Sijie Huang…·Charles S. Craik
This paper describes the discovery of new coronavirus MPro inhibitors with improved pharmacokinetics, broad-spectrum antiviral activity, and superior in vivo efficacy compared to existing drugs.
Mir Mubashir Khalid, Irene P. Chen, Frank W. Soveg…·Mélanie Ott
This study shows ORF8 suppresses viral particle production by interacting with Spike and causing Golgi fragmentation, supporting evolutionary pressure to delete ORF8 in SARS-CoV-2 variants.