Author

Megan Hopton

Boston UniversityORCID 0009-0006-4761-9849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aidan Holmes· 1 shared Audrey E. Van HeestiD· 1 shared Frances Liang· 1 shared Itay AlgoviD· 1 shared Liangliang HaoiD· 1 shared Xin X. ZhouiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioengineering

Aidan Holmes

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1 paper

Recent·Most cited

BioengineeringNature Chemical BiologyPeer-reviewedMay 11, 2026

A Tissue Proteolysis Activity Mapping and Substrate Discovery Platform for Identifying Novel Tumor-Activated Biosensors

Itay Algov, Audrey E. Van Heest, Megan Hopton…·Xin X. Zhou

This paper introduces PSurf, a platform for identifying tissue-specific protease sensors, and demonstrates its use in detecting tumor-specific proteolytic activity in lung tissue.

3 citationstop 3%

mouseproteomics

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