Author

Elisha Beebe

University of California San DiegoORCID 0009-0006-4921-7827Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 5 Organism:human· 5 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:scATAC-seq· 3 Assay:ATAC-seq· 2 Research Focus:fine-mapping· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Joshua ChiouiD· 5 shared Kyle J. GaultoniD· 5 shared Maike SanderiD· 4 shared Mei-Lin Okino· 4 shared Michael MilleriD· 4 shared Sebastian PreißliD· 4 shared Gaowei WangiD· 3 shared Katha Korgaonkar· 3 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Joshua ChiouORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

GenomicsScience AdvancesPeer-reviewedSep 10, 2025

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression

Rebecca L. Melton, Sara Jiménez, Weston S. Elison…·Kyle J. Gaulton

This study uses single-cell multiomics and spatial transcriptomics to identify gene regulatory programs in pancreatic cell types that drive type 1 diabetes progression.

33 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky

Systems BiologybioRxivPreprintDec 31, 2022

Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes

Gaowei Wang, Joshua Chiou, Chun Zeng…·Maike Sander

The paper integrates single-cell multiomic data with genetics to identify gene regulatory changes in beta cells associated with type 2 diabetes.

7 citations

humanscATAC-seq

𝕏 PostBluesky

GenomicsCell GenomicsPeer-reviewedNov 11, 2022

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

Paola Benaglio, Han Zhu, Mei-Lin Okino…·Kyle J. Gaulton

The paper identifies T1D risk genes and regulatory elements that influence beta cell survival under proinflammatory cytokine exposure using functional genomics and genetics.

33 citations

humanATAC-seq

𝕏 PostBluesky

GeneticsNaturePeer-reviewedMay 19, 2021

Large-scale genetic association and single cell accessible chromatin mapping defines cell type-specific mechanisms of type 1 diabetes risk

Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino…·Kyle J. Gaulton

This study combines large-scale GWAS and single-cell epigenomics to identify cell type-specific mechanisms of type 1 diabetes risk.

461 citationstop 1%

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsPLoS GeneticsPeer-reviewedMay 13, 2021

Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes

Anthony Aylward, Mei-Lin Okino, Paola Benaglio…·Kyle J. Gaulton

This study identifies glucocorticoid-responsive gene regulatory programs in pancreatic islets and links them to type 2 diabetes risk through chromatin and gene expression analysis.

31 citationstop 4%

humanATAC-seq

𝕏 PostBluesky