Author

Katha Korgaonkar

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 4 Approach:statistical model· 4 Assay:scATAC-seq· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:variant effect prediction· 2

Frequent Co-Authors

Kyle J. GaultoniD· 4 shared Michael MilleriD· 4 shared Sebastian PreißliD· 4 shared Elisha BeebeiD· 3 shared Joshua ChiouiD· 3 shared Maike SanderiD· 3 shared Paola Benaglio· 3 shared Ruth M. ElgamaliD· 3 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Kyle J. GaultonORCID

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Author profile →

4 papers

Recent·Most cited

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression

Rebecca L. Melton, Sara Jiménez, Weston S. Elison, Luca Tucciarone, Abigail Howell, Gaowei Wang, Denise A. Berti, Elisha Beebe, Michael Miller, Chun Zeng, Carolyn McGrail, Kennedy VanderStel, Katha Korgaonkar, Ruth M. Elgamal, Hannah M Mummey, , Kyle J. Gaulton

This study uses single-cell multiomics and spatial transcriptomics to identify gene regulatory programs in pancreatic cell types that drive type 1 diabetes progression.

Science Advances · Sep 10, 2025Peer-reviewedGenomics

Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

Hannah M Mummey, Weston S. Elison, Katha Korgaonkar, Ruth M. Elgamal, Parul Kudtarkar, Emily N. Griffin, Paola Benaglio, Michael Miller, Alokkumar Jha, Jocelyn E. Manning Fox, Mark I. McCarthy, Sebastian Preißl, Anna L. Gloyn, Patrick E. MacDonald, Kyle J. Gaulton

The paper uses single-cell multiome profiling to identify gene regulatory changes in pancreatic islets linked to diabetes risk factors like age, sex, and genetic variants.

bioRxiv · Aug 3, 2024 · PreprintGenomics

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

Paola Benaglio, Han Zhu, Mei-Lin Okino, Jian Yan, Ruth M. Elgamal, Naoki Nariai, Elisha Beebe, Katha Korgaonkar, Yunjiang Qiu, Margaret K. R. Donovan, Joshua Chiou, Gaowei Wang, Jacklyn M. Newsome, Jaspreet Kaur, Michael Miller, , Kyle J. Gaulton

The paper identifies T1D risk genes and regulatory elements that influence beta cell survival under proinflammatory cytokine exposure using functional genomics and genetics.

Cell Genomics · Nov 11, 2022Peer-reviewedGenomics

Large-scale genetic association and single cell accessible chromatin mapping defines cell type-specific mechanisms of type 1 diabetes risk

Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca L. Melton, Elisha Beebe, Paola Benaglio, Serina Huang, Katha Korgaonkar, Sandra Heller, Alexander Kleger, Sebastian Preißl, David U. Gorkin, Maike Sander, Kyle J. Gaulton

This study combines large-scale GWAS and single-cell epigenomics to identify cell type-specific mechanisms of type 1 diabetes risk.

Nature · May 19, 2021Peer-reviewedGenetics