The paper identifies two distinct eLPBChAT projections to the amygdala and bed nucleus of the stria terminalis that mediate methamphetamine withdrawal anxiety and relapse.

DOI 10.1101/2023.10.23.563030

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 12, 2021

A novel cholinergic neural pathway and its role in the drug relapse

Teng He, Wenwen Chen, Yu Fan…·Xiaowei Guan

The paper identifies a novel cholinergic pathway from eLPBChAT to CeAGABA that blocks methamphetamine-induced conditioned place preference in mice.

DOI 10.1101/2021.05.12.443812

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 20, 2020

Electro-acupuncture Alleviates METH Withdrawal-induced Spatial Memory Deficits by Restoring Astrocyte-drived Glutamate Uptake in dCA1

Pengbo Shi, Zhaosu Li, Xing Xu…·Xiaowei Guan

This study shows electro-acupuncture restores astrocyte-driven glutamate uptake in dCA1, reducing hyper-glutamatergic excitotoxicity and improving spatial memory deficits in METH withdrawal mice.

DOI 10.1101/2020.05.20.106153

mouseexperimental assay

𝕏 PostBluesky