Author

Andrew C. Mutter

City College of New YorkORCID 0009-0006-6470-7162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Aleksandr Uvaydov· 1 shared Bruce Allan PalfeyiD· 1 shared Carolyn E. LubneriD· 1 shared Eskil M. E. Andersen· 1 shared Mohammad Khan· 1 shared Ronald L. KoderiD· 1 shared Sara Morsi· 1 shared Sarah Beck· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Aleksandr Uvaydov

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintJun 28, 2026

Loop-Directed Cofactor Binding Enables Programmable Multico-factor Protein Design

Andrew C. Mutter, Aleksandr Uvaydov, Eskil M. E. Andersen…·Ronald L. Koder

This paper designs proteins with multiple cofactor binding sites by placing histidine ligands in loop regions, enabling precise control over cofactor positioning and function.

DOI 10.64898/2026.06.27.734619

protein structureexperimental assay

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