Ronald L. Koder

The paper develops a thermodynamic framework to classify elastic proteins by recoil mechanism using sequence-derived entropy estimates and identifies new candidates in the human proteome.

This paper designs proteins with multiple cofactor binding sites by placing histidine ligands in loop regions, enabling precise control over cofactor positioning and function.

This paper designs redox proteins with tunable electron transfer properties by replacing heme B with non-natural metalloporphyrins, achieving redox potential modulation of over 400 mV.