Author

Sean Myers

The Ohio State UniversityORCID 0009-0006-6548-6277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Guramrit SinghiD· 2 shared Ralf A. BundschuhiD· 2 shared Robert D. PattoniD· 2 shared Bayley N CarteriD· 1 shared Corinne DilsavoriD· 1 shared Debadrita Paul· 1 shared Lauren A. WoodwardiD· 1 shared Manu Sanjeev· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Guramrit SinghORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 30, 2025

PYM1 limits non-canonical Exon Junction Complex occupancy in a gene architecture dependent manner to tune mRNA expression

Manu Sanjeev, Lauren A. Woodward, Michael L. Schiff…·Guramrit Singh

This study shows PYM1 regulates EJC occupancy in a gene architecture-dependent manner, affecting mRNA stability and decay, and is exploited by flaviviruses to alter host mRNA regulation.

3 citations

humanmultiome

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 2, 2021

Mammalian UPF3A and UPF3B activate NMD independently of their EJC binding

Zhongxia Yi, René M. Arvola, Sean Myers…·Guramrit Singh

The paper shows that UPF3A and UPF3B can activate NMD independently of EJC binding in human cells, challenging the idea that UPF3 is solely a bridge between the EJC and UPF complex.

3 citations

humanexperimental assay

𝕏 PostBluesky