Author

Shelly Hamer-Rogotner

Weizmann Institute of ScienceORCID 0009-0006-7228-9589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Orly DymiD· 2 shared Andrej BergiD· 1 shared Ariel AfekiD· 1 shared Dina ListoviD· 1 shared Eva VosiD· 1 shared Gyula HoffkaiD· 1 shared Karn Onoon· 1 shared Lihee GivoniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 30, 2025

Systematic DNA nicking reveals the structural logic of protein recognition

Yumi Minyi Yao, Michael O’Hagan, Karn Onoon…·Ariel Afek

This study introduces PIC-NIC, a method to systematically perturb DNA binding sites without altering base sequences, revealing how DNA backbone structure influences transcription factor binding.

DOI 10.1101/2025.06.30.662289

humanDNA methylation

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BiochemistryNaturePeer-reviewedJun 18, 2025

High-efficiency Kemp eliminases by complete computational design

Dina Listov, Eva Vos, Gyula Hoffka…·Sarel Jacob Fleishman

This paper presents a computational design of high-efficiency Kemp eliminases with unprecedented catalytic efficiency and stability through de novo enzyme design.

59 citationstop 1%

protein structuredeep learning

𝕏 PostBluesky