Author

Christopher M. Silvestri

McMaster UniversityORCID 0009-0006-7480-5313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Brian Dennis LichtyiD· 1 shared Christopher L. BakeriD· 1 shared Claire G. Morris· 1 shared Derek T. CummingsiD· 1 shared Joanne A. HammilliD· 1 shared John C. Bell· 1 shared Jonathan L. BramsoniD· 1 shared Mira IshakiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Brian Dennis LichtyORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintNov 29, 2024

Boosting of CAR-T cells with rhabdovirus is limited by type I interferon and rapid contraction

Rebecca Burchett, Claire G. Morris, Mira Ishak…·Jonathan L. Bramson

This study shows that boosting CAR-T cells with a VSV vaccine encoding the CAR-target leads to robust expansion but rapid contraction, while TCR-mediated boosting improves persistence and tumor eradication.

DOI 10.1101/2024.11.29.626103

mousebulk RNA-seq

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