Author

Jacquelyn M. Curtis

Harvard UniversityORCID 0009-0006-7828-9272Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:imaging· 1

Frequent Co-Authors

Ryan Bruce CorcoraniD· 2 shared Andrea I. McClatcheyiD· 1 shared Catherin Movsessian· 1 shared Christine Chiasson-MacKenzieiD· 1 shared David T. MyersiD· 1 shared Edmond WongiD· 1 shared Emily Wright· 1 shared Ferran Fece de la CruziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Ryan Bruce CorcoranORCID

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2 papers

Recent·Most cited

Genetic dissection of DNA damage response pathways reveals divergent modulation of PD-1 blockade response in colorectal cancer

Ferran Fece de la Cruz, Edmond Wong, Haley Barnes, Katerina A. Fella, Jacquelyn M. Curtis, Sarah Phat, David T. Myers, Parasvi S. Patel, Jonathan Braverman, Ömer H. Yilmaz, Ryan Bruce Corcoran

This study identifies DDR gene alterations that modulate PD-1 blockade response in MSS colorectal cancer, showing that some defects enhance immunotherapy while others reduce benefit.

bioRxiv · Oct 6, 2026 · PreprintCancer Biology

Quantitative imaging of schwannoma captures heterogeneity and accelerates preclinical testing, exposing distinct therapeutic signatures

Emily Wright, Jérémie Vitte, Sara I. Veiga, Sarah Bushnell, Catherin Movsessian, Youwen Zhang, Jacquelyn M. Curtis, Ryan Bruce Corcoran, Shannon L. Stott, Marco Giovannini, Christine Chiasson-MacKenzie, Andrea I. McClatchey

This study uses quantitative imaging to analyze schwannoma heterogeneity and test drugs in a mouse model, revealing distinct therapeutic response signatures.

bioRxiv · Sep 30, 2026 · PreprintCancer Biology