Guadalupe Pereyra

This study shows SFRP1 drives astrocytic glycolytic activation during neuroinflammation, enhancing metabolic flexibility to meet energy demands.

This study shows that SFRP1 overexpression in astrocytes causes synaptic dysfunction and memory impairment in mice, suggesting SFRP1 as a therapeutic target for Alzheimer's disease.

This study shows that SFRP1 from astrocytes promotes microglial activation in acute and chronic neuroinflammation, suggesting it as a therapeutic target.

This study shows that Sfrp1 deficiency leads to photoreceptor degeneration and increased light-induced damage in mice, highlighting SFRP1's role in maintaining outer limiting membrane integrity.