Reduced D-serine levels drive enhanced non-ionotropic NMDA receptor signaling and destabilization of dendritic spines in a mouse model for studying schizophrenia
Deborah K. Park, Samuel Petshow, Margarita Anisimova…·Karen Zito
The paper shows that reduced D-serine in a schizophrenia mouse model enhances non-ionotropic NMDAR signaling, leading to dendritic spine destabilization.