Eden V. Barragan

D-Serine inhibits non-ionotropic NMDA receptor signaling

This study shows that D-serine inhibits non-ionotropic NMDA receptor signaling and plasticity by blocking glutamate-induced conformational changes in the absence of co-agonist.

Reduced D-serine levels drive enhanced non-ionotropic NMDA receptor signaling and destabilization of dendritic spines in a mouse model for studying schizophrenia

The paper shows that reduced D-serine in a schizophrenia mouse model enhances non-ionotropic NMDAR signaling, leading to dendritic spine destabilization.

Postsynaptic serine racemase regulates NMDA receptor function

This study shows that postsynaptic serine racemase regulates NMDA receptor function in mouse hippocampal neurons, with age-dependent effects on long-term potentiation and GluN2B expression.