GeneticsbioRxivPreprint
Synthetic engineering demonstrates that synergy among enhancers involves an increase in transcriptionally productive enhancer-gene contacts
Endika Haro, Marianna Iliadou, Shyam Ramasamy…·Álvaro Rada-Iglesias
The paper uses synthetic enhancer engineering in mESCs to show that enhancer clusters increase transcriptionally productive enhancer-gene contacts through enhanced RNA Polymerase II pause release.
1 citation