Author

Nicholas Rohlfes

Loyola University ChicagoORCID 0009-0006-9675-4932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alan N. EngelmaniD· 2 shared Edward M. CampbelliD· 2 shared Parmit Kumar SinghiD· 2 shared Rajalingam RadhakrishnaniD· 2 shared Adarsh DharaniD· 1 shared Bjarki Arnarson· 1 shared Chandravanu DashiD· 1 shared Christopher AikeniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Alan N. EngelmanORCID

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2 papers

Recent·Most cited

BiochemistryJournal of VirologyPeer-reviewedApr 9, 2025

CPSF6 Promotes HIV-1 Preintegration Complex Function

Evan Chaudhuri, Sooin Jang, Rajasree Chakraborty…·Chandravanu Dash

This study shows CPSF6 promotes HIV-1 preintegration complex function by enhancing viral DNA integration into gene-dense regions and restoring integration activity when added back to mutant cells.

7 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyPLoS PathogensPeer-reviewedJan 17, 2025

The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection

Nicholas Rohlfes, Rajalingam Radhakrishnan, Parmit Kumar Singh…·Edward M. Campbell

This study investigates how the nuclear localization signal (NLS) of CPSF6 influences HIV-1 infection after nuclear import, showing that some NLSs impair viral integration.

8 citations

humanexperimental assay

𝕏 PostBluesky