Author

Yen-Yun Chen

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anne L. CalofiD· 2 shared Arthur D. LanderiD· 2 shared Ebony FlowersiD· 2 shared Kyoko YokomoriiD· 2 shared Richard Chien· 2 shared Rosaysela SantosiD· 2 shared Shimako KawauchiiD· 2 shared Alexander R. Ball· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anne L. CalofORCID

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2 papers

Recent·Most cited

The cohesin loader NIPBL interacts with pre-ribosomal RNA and treacle to regulate ribosomal RNA synthesis

Xiangduo Kong, Yen-Yun Chen, Jianhuang Lin, Ebony Flowers, Eric L. Van Nostrand, Steven M. Blue, Jonathan Chau, Christopher I-Hsing, Isaiah Mohr, Ryan Thai, Chengguo Yao, Alexander R. Ball, Richard Chien, Shimako Kawauchi, Rosaysela Santos, , Kyoko Yokomori

This study identifies NIPBL's interaction with RNA and treacle in regulating pre-rRNA transcription and nucleolar organization.

bioRxiv · Jun 4, 2019 · PreprintMolecular Biology

The Effect Of Nipped-B-Like (Nipbl) Haploinsufficiency On Genome-Wide Cohesin Binding And Target Gene Expression: Modeling Cornelia de Lange Syndrome

Daniel A. Newkirk, Yen-Yun Chen, Richard Chien, Weihua Zeng, Jacob Biesinger, Ebony Flowers, Shimako Kawauchi, Rosaysela Santos, Anne L. Calof, Arthur D. Lander, Xiaohui S. Xie, Kyoko Yokomori

This study examines how Nipbl haploinsufficiency affects cohesin binding and gene expression in mice, linking reduced cohesin function to CdLS-related gene dysregulation.

Clinical Epigenetics · Aug 25, 2017Peer-reviewedDevelopmental Biology