Garrick Chang

This study shows that TYK2 inhibitors reduce islet inflammation and delay type 1 diabetes onset in mice by modulating immune and endocrine responses.

This study shows that miR-146a-5p overexpression in beta cells under inflammatory stress causes mitochondrial dysfunction and apoptosis, while its inhibition reverses these effects.

This study shows that HDI sodium butyrate improves β cell function and calcium signaling in diabetes by restoring STIM1 and SOCE, and inhibiting GSK-3 through AKT.