Author

Lena M. Kallweit

University of DenverORCID 0009-0007-2452-8300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Scott A. HorowitziD· 2 shared Anah Gilmore· 1 shared Ann‐Charlotte GranholmiD· 1 shared Daniel ParedesiD· 1 shared Eric Daniel HamlettiD· 1 shared Hannah Saternos· 1 shared Kevin M Reynolds CaicedoiD· 1 shared Luke T. Kelly· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

Scott A. HorowitzORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 4, 2025

G-quadruplex sequence dictates tau oligomerization and fibril morphology

Lena M. Kallweit, Luke T. Kelly, Kevin M Reynolds Caicedo…·Scott A. Horowitz

This study shows that G-quadruplex sequences influence tau oligomerization and fibril morphology in human hippocampal aggregates.

DOI 10.64898/2025.12.02.691785

humanexperimental assay

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedFeb 24, 2025

Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease

Lena M. Kallweit, Eric Daniel Hamlett, Hannah Saternos…·Scott A. Horowitz

This study finds increased RNA G-quadruplex accumulation in aging and Alzheimer's disease hippocampus, linking it to tau aggregation and APOE genotype.

11 citations

humanprotein structure

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