Author

Carrie A. Malcom

University of Kansas Medical CenterORCID 0009-0007-2939-8883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Anamika Ratri· 2 shared Jay L. VivianiD· 2 shared M. A. Karim RumiiD· 2 shared Patrick E. FieldsiD· 2 shared Shaon BoroshaiD· 2 shared Timothy A. FieldsiD· 2 shared V. Praveen ChakravarthiiD· 2 shared Joanna Piasecka‐Srader· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersDevelopmental Biology

Anamika Ratri

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintOct 15, 2020

DOT1L primarily acts as a transcriptional repressor in hematopoietic progenitor cells

Shaon Borosha, Anamika Ratri, Sami M. Housami…·Patrick E. Fields

This study investigates the role of DOT1L in hematopoietic progenitor cells by analyzing transcriptomes of knockout and mutant models, revealing its function as a transcriptional repressor.

2 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintSep 30, 2020

The Role of DOT1L Methyltransferase Activity in Fetal Hematopoiesis

Carrie A. Malcom, Joanna Piasecka‐Srader, V. Praveen Chakravarthi…·Patrick E. Fields

This study shows that DOT1L methyltransferase activity is essential for early murine hematopoiesis, as its loss causes embryonic lethality and genomic instability in hematopoietic progenitors.

5 citations

mouseexperimental assay

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