M. A. Karim Rumi

This study identifies age-related changes in transcript variants in mouse ovaries, revealing that differential expression of alternative transcripts is often overlooked by traditional gene expression analyses.

The paper shows that ignoring transcript variants in RNA-Seq analysis leads to inaccurate conclusions about gene expression, as over 80% of transcript expression changes are missed when using gene-level data alone.

This study identifies dysregulated epigenetic regulators and transcription factors in ErβKO rat ovaries during postnatal development, leading to altered follicle activation and downstream gene expression.

This study identifies ESR2 as a regulator of Indian hedgehog signaling in neonatal rat ovaries, showing its role in controlling primordial follicle activation.

The paper identifies ERβ-regulated genes in granulosa cells that are essential for ovarian follicle maturation beyond the antral stage, revealing both known and novel genes involved in this process.

The paper investigates the role of ovarian KISS1 signaling in oocyte maturation and shows that ERβ regulates KISS1 expression in granulosa cells, which is essential for gonadotropin-induced oocyte maturation.

This study investigates the role of DOT1L in hematopoietic progenitor cells by analyzing transcriptomes of knockout and mutant models, revealing its function as a transcriptional repressor.

This study shows that DOT1L methyltransferase activity is essential for early murine hematopoiesis, as its loss causes embryonic lethality and genomic instability in hematopoietic progenitors.

The paper identifies differentially expressed transposable element families in mouse stem cell lineages and suggests their potential roles in lineage differentiation.

This study identifies SATB1-regulated genes in mouse ectoplacental cones and shows their role in trophoblast differentiation and placental development.

The paper identifies a long-range chromatin interaction that regulates Satb1 expression in trophoblast stem cells through ELF5 and SATB protein interactions.

This study shows that ESR2 prevents excessive activation of primordial follicles, and its disruption leads to premature ovarian senescence and reduced AMH and estradiol levels.

This study shows that 17α Estradiol enhances plasticity in the adult amblyopic visual cortex by increasing synaptic size and promoting experience-dependent plasticity.