Developmental BiologybioRxivPreprint
The Role of DOT1L Methyltransferase Activity in Fetal Hematopoiesis
Carrie A. Malcom, Joanna Piasecka‐Srader, V. Praveen Chakravarthi…·Patrick E. Fields
This study shows that DOT1L methyltransferase activity is essential for early murine hematopoiesis, as its loss causes embryonic lethality and genomic instability in hematopoietic progenitors.
5 citations