Author

Sarah M. Granger

University of SheffieldORCID 0009-0007-3783-4307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Laura FerraiuoloiD· 2 shared Allan Christian ShawiD· 1 shared Amy F. A. KeerieiD· 1 shared Anne Phelan· 1 shared Chloe F. AlleniD· 1 shared Daniel P. SmithiD· 1 shared David W. SheppardiD· 1 shared Heather MortiboysiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Laura FerraiuoloORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 6, 2025

Artificial intelligence-augmented drug discovery identifies gefitinib as a potential treatment for ALS

Monika A. Myszczynska, Matthew J. Stopford, Nóra M. Márkus…·Laura Ferraiuolo

This paper uses AI to identify gefitinib as a potential ALS treatment, showing it protects motor neurons and reduces TDP-43 fragments in vitro and in vivo.

2 citations

humanmouse

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NeurosciencebioRxivPreprintFeb 28, 2025

C9orf72-ALS mutation drives mitophagy impairments in iNeurons

James Lee, Sarah M. Granger, Katie Roome…·Heather Mortiboys

This study shows that C9orf72-ALS mutation impairs mitophagy in iNeurons by reducing autophagosome production and ULK1 recruitment to mitochondria.

DOI 10.1101/2025.02.28.640849

humanexperimental assay

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