Author

Leilei Yang

Chinese Academy of SciencesORCID 0009-0007-4093-0332Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

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Guanghou ShuiiD· 1 shared Jingjing LiangiD· 1 shared Jinglin ZhuiD· 1 shared Mei DingiD· 1 shared Sin Man LamiD· 1 shared Xun HuangiD· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperDevelopmental Biology

Guanghou ShuiORCID

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Developmental BiologybioRxivPreprintApr 10, 2022

Contrasting effects of reduced phosphatidylcholine synthesis in absence of seipin: embryonic lethality goes down while lipid droplets get even larger

Jinglin Zhu, Sin Man Lam, Leilei Yang…·Xun Huang

The paper identifies nhr-114 and spin-4 as suppressors of seip-1 embryonic lethality in C. elegans, showing that reducing phosphatidylcholine synthesis suppresses lethality but worsens lipid droplet abnormalities.

DOI 10.1101/2022.04.10.487805

C. elegansstatistical model

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