Author

Sho Takeuchi

Kyoto UniversityORCID 0009-0007-4410-9293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Ayuna TsutsumiiD· 1 shared Haruo OgawaiD· 1 shared Hiroyuki KagechikaiD· 1 shared Kazuyoshi MurataiD· 1 shared Nagomi KurebayashiiD· 1 shared Raymond N. Burton‐SmithiD· 1 shared Ryosuke IshidaiD· 1 shared Takashi MurayamaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ayuna TsutsumiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMay 23, 2026

Structural basis for Ca2+-dependent allosteric modulation of cardiac ryanodine receptor by Ryanozole

Yuya Otori, Takashi Murayama, Ayuna Tsutsumi…·Haruo Ogawa

This study defines the mechanism of Ryanozole's Ca2+-dependent modulation of RyR2 using cryo-EM, mutagenesis, and functional assays, revealing its structural basis for CPVT therapy.

DOI 10.64898/2026.05.11.724262

humanstructural biology

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