Author

Jan-Daniël de Leede-Scheven

Royal Netherlands Academy of Arts and SciencesORCID 0009-0007-4877-8128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Katharina F. SonneniD· 2 shared Sonja D. C. WeteringsiD· 2 shared Alexander van OudenaardeniD· 1 shared Amir GiladiiD· 1 shared Balaji Srinivasan· 1 shared Dimitri FabrègesiD· 1 shared Esther J. M. LieftingiD· 1 shared Eveline F. Ilcken· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Katharina F. SonnenORCID

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2 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedOct 25, 2026

Spatiotemporal proteomics reveals dynamic antagonistic gradients shaping signalling waves

Wilke H. M. Meijer, Virginia Andrade, Suzan Stelloo…·Katharina F. Sonnen

The paper uses a microfluidics and proteomics approach to study dynamic protein gradients in mouse embryos, revealing antagonistic ligand-receptor patterns that regulate Wnt oscillations and somite formation.

1 citation

mouseproteomics

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Cell BiologySciencePeer-reviewedOct 15, 2026

NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis

Sonja D. C. Weterings, Hiromune Eto, Jan-Daniël de Leede-Scheven…·Katharina F. Sonnen

The paper shows that NOTCH-driven Hes1 oscillations with different periods control cell fate decisions in intestinal stem cells, influencing secretory and absorptive lineage commitment.

18 citationstop 1%

mousescRNA-seq

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