Ji Hun Kim

The paper shows that in fragile X syndrome, long-range heterochromatinization of distal synaptic genes with STR instability is reversible by overexpression of a pre-mutation-length CGG tract.

This paper introduces LADL, a light-activated system to dynamically control chromatin looping, showing it can redirect enhancer-promoter interactions and alter gene expression within four hours.

The paper introduces 5C-ID, a method that improves resolution and reduces noise in chromatin loop detection compared to standard 5C, enabling high-resolution 3D genome maps at lower cost than Hi-C.