Cohesin-mediated loop anchors confine the location of human replication origins
Daniel J. Emerson, Peiyao A Zhao, Ashley L. Cook, R. Jordan Barnett, Kyle N. Klein, Dalila Saulebekova, Chunmin Ge, Linda Zhou, Zoltán Simándi, Miriam K. Minsk, Katelyn R. Titus, Weitao Wang, Wanfeng Gong, Di Zhang, Liyan Yang, , Jennifer E. Phillips‐Cremins
This study shows that cohesin-mediated loops in G1 phase determine the genomic location of replication origins in S phase by anchoring replication initiation zones.
Nature · Jun 8, 2022Peer-reviewedGenomics