Ajesh Jacob

The paper develops SA-eGRASP to map and track potentiated synapses in the mouse hippocampus following learning and uses it to study long-term synaptic dynamics.

The paper characterizes the PSD-95 interactome of hippocampal synapses potentiated by an in vivo learning task using a genetically encoded probe and mass spectrometry.

The paper shows that potentiated dendritic spines in hippocampal neurons are spatially distributed differently during memory encoding and recall phases.