Francesco Gobbo

Navigational strategy dictates hippocampal representation of space in an everyday memory task

This study investigates how hippocampal representations of space differ based on navigational strategy in rats performing memory tasks.

The PSD-95 interactome of hippocampal synapses potentiated in response to an in vivo learning task

The paper characterizes the PSD-95 interactome of hippocampal synapses potentiated by an in vivo learning task using a genetically encoded probe and mass spectrometry.

Distinct spatial distribution of potentiated dendritic spines in encoding- and recall-activated hippocampal neurons

The paper shows that potentiated dendritic spines in hippocampal neurons are spatially distributed differently during memory encoding and recall phases.

Opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures

This study uses live human brain slice cultures to show that physiological and pathological amyloid-beta have opposing effects on synapses, with physiological levels enhancing synaptic transcripts and pathological levels causing synaptic loss.

Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease

The paper identifies transmembrane protein 97 as a synaptic receptor for amyloid beta in human Alzheimer's disease using advanced microscopy and drug intervention studies.

Activity-dependent expression of reporter proteins at dendritic spines for synaptic activity mapping and optogenetic stimulation

The paper introduces a method to express light-sensitive proteins at active dendritic spines to map and stimulate synaptic activity.