Priyanka P. Brahmachary

This study examines how mechanical injury alters metabolism in bovine and human chondrocytes, revealing differences in oxygen consumption and glutamine accumulation between healthy and osteoarthritic cells.

This study investigates how cyclical compression and shear deformations affect central metabolites in chondrocytes, showing changes in metabolites that could inform therapeutic mechanotransduction for cartilage repair.

This study compares viscoelastic recovery time of chondrocytes from monolayer and alginate cultures, finding significant differences linked to pericellular matrix properties.

This study identifies sex-specific metabolic changes in injured joints of male and female mice using MALDI-MSI and metabolomics, revealing tissue-specific and spatially dependent metabolic signatures.

This study develops a 3D culture system for chondrocytes that supports pericellular matrix development and enables mechanotransduction studies through metabolomic profiling.

This study examines metabolic changes in chondrocytes under simulated microgravity, finding metabolic shifts linked to early osteoarthritis.

This study compares metabolomic profiles of healthy and osteoarthritic human cartilage to identify disease-associated metabolic endotypes and pathways.