Cell BiologyeLifePeer-reviewed
Contractile perinuclear actomyosin network promotes peripheral and polar chromosome interaction with the mitotic spindle
Nooshin Sheidaei, John K. Eykelenboom, Zuojun Yue…·Tomoyuki U Tanaka
The paper shows that PANEM contraction repositions peripheral and polar chromosomes to enhance their interaction with the mitotic spindle, ensuring correct segregation and reducing chromosomal instability in cancer cells.
DOI 10.7554/elife.110952.3