Alexander S. Little

This study shows dietary glutamate influences ImP production via microbial competition, affecting glucose tolerance and systemic ImP levels.

The paper identifies a novel gut bacterial pathway for steroid hormone metabolism and shows its impact on drug efficacy in Crohn's disease.

This study identifies DNA-utilization loci in gut Bacteroidales that metabolize exogenous DNA into deaminated nucleobases, revealing a conserved pathway with implications for host-microbe interactions.

This paper introduces SCALES, a method that extracts hierarchical protein interaction networks from bacterial proteome variation patterns, revealing new genetic factors in Pseudomonas aeruginosa motility.