Cancer BiologyACS Chemical BiologyPeer-reviewed
Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer
Fabiana Izidro Layng, Huiyu Ren, Nicole A. Bakas…·Nicholas D. P. Cosford
The paper reports the design, synthesis, and characterization of new ULK1/2 inhibitors that inhibit autophagy and upregulate MHC I in NSCLC cells, supporting their potential as cancer therapeutics.
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