ImmunologybioRxivPreprint
HLA Alleles Imprint Distinct Biases in the Usage Preferences of TCR Vβ segments
Leonardo V. Castorina, Matthew T. Noakes, Lorenzo Pisani…·Harus Jabran Zahid
This study identifies HLA allele-specific biases in TCR Vβ usage, showing germline-encoded preferences shape TCR-HLA compatibility and influence TCR-pHLA specificity.
DOI 10.64898/2026.02.19.706729