Author
National Institutes for Food and Drug ControlORCID 0009-0008-0820-0038Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Zhuo Huang, Yanan Chu, Yabin Tian…·Jie Huang
This paper benchmarks how reference genome choice affects human genome interpretation by comparing T2T references and finding ancestry-matched references provide more accurate variant discovery.
Yanan Chu, Zhuo Huang, Changjun Shao…·Yu Kang
The paper introduces a support-based validation framework to correct assembly errors in diploid genomes using independent sequencing evidence.
Tengxue Lou, Dongming Fang, Guigao Lin…·Jie Huang
The paper presents haplotype-resolved T2T assemblies of two MZ twins, revealing genomic and epigenetic divergence, including structural variation and DNA methylation differences.