Lele Xu

This study examines temporal changes in hippocampal extracellular matrix and glial reorganization following peripheral injury, identifying matrix biomechanics as a regulator of microglial function.

This study identifies metabolic partnerships between medulloblastoma and macrophages that drive leptomeningeal metastases and suggests targeting the CXCL12-SCARB1-cholesterol axis as a therapeutic strategy.

This paper introduces PLANCK, a label-free super-multiplex optical imaging technique that uses AI to decode vibrational images into molecular species, achieving high specificity and scalability.

This study identifies RXR signaling as a mediator of lipid metabolism in leptomeningeal metastatic cancer cells, revealing a potential therapeutic target.