Ye He

This study identifies metabolic partnerships between medulloblastoma and macrophages that drive leptomeningeal metastases and suggests targeting the CXCL12-SCARB1-cholesterol axis as a therapeutic strategy.

This paper introduces PLANCK, a label-free super-multiplex optical imaging technique that uses AI to decode vibrational images into molecular species, achieving high specificity and scalability.

This study identifies RXR signaling as a mediator of lipid metabolism in leptomeningeal metastatic cancer cells, revealing a potential therapeutic target.

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

This study identifies a role for the Drosophila voltage-gated sodium channel, paralytic, in regulating neural progenitor proliferation and tumor suppression.