YoungUk Jang

This paper develops a tumor-targeting engineered bacterium that improves therapeutic efficacy and safety in cancer treatment.

This study identifies Tregs as an immunometabolic checkpoint that limits HSL activation and lipolysis via IL-10-IL10R signaling in adipose tissue.

This study identifies Tetherin as an immunometabolic checkpoint in adipocytes that restricts type I interferon signaling while preserving glycolytic capacity, improving metabolic homeostasis.

This paper identifies a brainstem circuit involving PAC1R in preBotC neurons that links stress responses to metabolic regulation, showing its role in fear, respiration, and energy expenditure.

This study engineers probiotic E. coli to deliver neoantigen peptides, enhancing T cell immunity and reducing tumor growth in mice.