Cell BiologyScience AdvancesPeer-reviewed
The AID2 system offers a potent tool for rapid, reversible, or sustained degradation of essential proteins in live mice
Valentina C. Sladky, Margaret A. Strong, Daniel Tapias-Gomez…·Andrew Jon Holland
The paper introduces an optimized AID system for reversible and sustained protein degradation in live mice, demonstrating its effectiveness in degrading CEP192 and causing cell division failure.
7 citations