Erkan Narmanli

The paper shows EWSR1::FLI1 fusion drives the production of cancer-specific neoproteins in Ewing sarcoma, revealing a reversible dark proteome with therapeutic potential.

This paper introduces an alignment-last approach to transcriptomic analysis, enabling rapid biomarker discovery by using reads directly and revealing new transposable-element signatures and prognostic reads in cancer.

The paper uses multi-omics analysis to compare malignant and normal uveal melanocytes, identifying genomic instability and a BAP1 promoter deletion as key features of uveal melanoma.