Author

Alexandre Lanau

InsermORCID 0000-0002-7304-6208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:imputation· 1

Frequent Co-Authors

Joshua J. WaterfalliD· 2 shared Erkan NarmanliiD· 1 shared Mara NeacsuiD· 1 shared Maria K. KoshkinaiD· 1 shared Nicolas PerriniD· 1 shared Nicolas ServantiD· 1 shared Philippe Martin· 1 shared Pierre Fumeron· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBioinformatics

Joshua J. WaterfallORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 3, 2026

An alignment-last approach enables rapid transcriptomic biomarker discovery in large cohorts

Erkan Narmanli, Alexandre Lanau, Mara Neacsu…·Joshua J. Waterfall

This paper introduces an alignment-last approach to transcriptomic analysis, enabling rapid biomarker discovery by using reads directly and revealing new transposable-element signatures and prognostic reads in cancer.

1 citation

humanbulk RNA-seq

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BioinformaticsBioinformatics AdvancesPeer-reviewedDec 26, 2024

pyALRA: python implementation of low-rank zero-preserving approximation of single cell RNA-seq

Alexandre Lanau, Joshua J. Waterfall

pyALRA provides a Python implementation of ALRA for imputing dropouts in single-cell RNA-seq with improved speed and memory efficiency.

DOI 10.1093/bioadv/vbaf279

scRNA-seqstatistical model

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