Author

Lois M. Kelly

InsermORCID 0009-0008-2950-3089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandre PuissantiD· 1 shared Amy E. StewartiD· 1 shared Arnaud JacqueliD· 1 shared Ben Zolyomi· 1 shared Benoît VianayiD· 1 shared Camille LobryiD· 1 shared Cécile Culeux· 1 shared Christopher B. NewgardiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alexandre PuissantORCID

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2 papers

Recent·Most cited

Cancer BiologyEMBO ReportsPeer-reviewedJun 11, 2025

AML patient blasts exhibit polarization defect upon interaction with bone marrow stromal cells.

Khansa Saadallah, Benoît Vianay, Louise Bonnemay…·Manuel Théry

This study shows AML blasts fail to polarize when interacting with healthy stromal cells, and AML-derived stromal cells impair polarization of healthy HSPCs and AML blasts.

2 citations

humanexperimental assay

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Cancer BiologybioRxivPreprintFeb 26, 2025

Pathway Coessentiality Mapping Reveals Complex II is Required for de novo Purine Biosynthesis in Acute Myeloid Leukemia

Amy E. Stewart, Derek K. Zachman, Pol Castellano‐Escuder…·Matthew D. Hirschey

The paper identifies Complex II's role in de novo purine biosynthesis in AML using CRISPR and metabolomic data, showing it as a therapeutic target.

2 citations

mousemetabolomics

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