Marek J. van Oostrom

The paper uses a microfluidics and proteomics approach to study dynamic protein gradients in mouse embryos, revealing antagonistic ligand-receptor patterns that regulate Wnt oscillations and somite formation.

The paper shows that coupling cell proliferation to the segmentation clock ensures uniform PSM growth and precise somite scaling in mouse embryos.

This study uses single-cell tracking to analyze Hes1 dynamics in mouse embryos, revealing distinct oscillation patterns in presomitic mesoderm and preneural tube cells.

This study develops a genetic tool to spatio-temporally perturb FGF signaling in zebrafish and demonstrates its use in studying cell-autonomous requirements for FGF signaling in pectoral fin development.